supplement

Methylene Blue

Also known as: MB

Chemical structure of Methylene Blue (PubChem CID 6099)
Structure via PubChem
Half-life
14 h
Typical timing
morning
Food rule
either
Default unit
mg

Studied for

Overview

Methylene Blue (MB) is a synthetic organic compound that belongs to the phenothiazine class. It is perhaps best known for its historical use as a dye for staining tissues and bacteria, and as a treatment for methemoglobinemia. However, in recent decades, research has expanded its potential applications, particularly in the fields of neuroscience and mitochondrial health. It is characterized by its deep blue color in solution. MB has a wide range of biological activities, acting as an electron carrier within the mitochondria, an antioxidant, and a modulator of various signaling pathways. It has been investigated for its potential neuroprotective effects, cognitive enhancement, and anti-aging properties. While Methylene Blue is available as a supplement, it is also used as a prescription medication for specific medical conditions. It is important to distinguish between these uses and to understand that the information provided here pertains to its general properties and research, and not to specific medical treatments.

Deep dive

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Known interactions

  • Category rule: glp1 × supplement
    Note

    GLP-1 medications slow stomach emptying, changing how/when oral supplements absorb; rapid weight loss raises the importance of protein and micronutrients.

    Time oral supplements when nausea is lowest; prioritize protein and micronutrients; discuss with your provider.

  • Category rule: supplement × medication
    Note

    Some supplements change how the body processes medications (absorption, liver enzymes, or additive effects).

    Specific pairs are checked against a licensed drug database and shown with their own severity. Always confirm with your provider or pharmacist.

Frequently asked

Sources referenced

["PubChem (National Center for Biotechnology Information)", "DrugBank Online", "FDA label (for medical grade Methylene Blue)", "EMA SmPC (European Medicines Agency Summary of Product Characteristics)", "MedlinePlus (National Library of Medicine)", "NIH Office of Dietary Supplements (general information on dietary supplements)"]

Stackwise compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.

Related compounds

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Related benefits

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