Cordyceps, a genus of parasitic fungi that grows on insect larvae, has a long history of use in traditional Chinese medicine. While there are over 400 species of Cordyceps, two species, *Cordyceps sinensis* (now *Ophiocordyceps sinensis*) and *Cordyceps militaris*, are most commonly studied and used in supplements. Traditionally, it has been valued for its purported ability to enhance energy, improve stamina, and support various bodily functions. In modern contexts, particularly in sports nutrition, Cordyceps has gained attention for its potential to improve exercise performance and reduce fatigue.
Cordyceps supplements are typically derived from cultivated *Cordyceps militaris* or a mycelial extract of *Cordyceps sinensis* known as CS-4. These cultivated forms ensure a consistent product and avoid overharvesting the wild varieties. The mushroom contains a variety of bioactive compounds, including cordycepin, adenosine, polysaccharides, and ergosterols, which are believed to contribute to its observed effects. Research into Cordyceps is ongoing, with studies exploring its impact on athletic performance, immune function, and anti-inflammatory properties.
Deep dive
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Known interactions
Category rule: glp1 × supplement
Note
GLP-1 medications slow stomach emptying, changing how/when oral supplements absorb; rapid weight loss raises the importance of protein and micronutrients.
Time oral supplements when nausea is lowest; prioritize protein and micronutrients; discuss with your provider.
Category rule: supplement × medication
Note
Some supplements change how the body processes medications (absorption, liver enzymes, or additive effects).
Specific pairs are checked against a licensed drug database and shown with their own severity. Always confirm with your provider or pharmacist.
Frequently asked
Sources referenced
["PubChem (National Library of Medicine)", "Cochrane Library (general adaptogen review, not specific Cordyceps review)", "MedlinePlus (for general supplement guidance)", "Journal of Alternative and Complementary Medicine", "Journal of Dietary Supplements"]
Stackwise compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.
Related compounds
Others in the supplement category or studied for the same goals.