Zinc bisglycinate is a chelated form of the essential trace mineral zinc, where zinc ions are bound to two molecules of the amino acid glycine. This chelation process is designed to enhance the absorption and bioavailability of zinc in the body compared to other forms, such as zinc oxide or zinc gluconate (PubChem). As an essential mineral, zinc plays a crucial role in numerous physiological processes, including immune function, cell division, wound healing, protein synthesis, and DNA synthesis (National Institutes of Health Office of Dietary Supplements). It is a cofactor for over 300 enzymes involved in metabolic reactions. Dietary sources of zinc include red meat, poultry, seafood (especially oysters), dairy products, nuts, legumes, and whole grains. Despite its presence in various foods, zinc deficiency can occur, particularly in individuals with certain dietary restrictions (e.g., vegetarians, vegans), gastrointestinal disorders, or those with increased needs, such as pregnant women and children (MedlinePlus). Zinc bisglycinate is commonly used as a dietary supplement to address or prevent zinc deficiency and to support overall health.
Deep dive
Tap a section to expand.
Known interactions
Compound-pair rule
Caution
Divalent cations chelate levothyroxine in the gut and reduce absorption by up to 30%.
Take levothyroxine on empty stomach; separate mineral supplements by at least 4 hours.
Suggested separation: 4 h
Compound-pair rule
Caution
Divalent cations chelate levothyroxine in the gut and reduce absorption by up to 30%.
Take levothyroxine on empty stomach; separate mineral supplements by at least 4 hours.
Suggested separation: 4 h
Compound-pair rule
Caution
Divalent cations chelate levothyroxine in the gut and reduce absorption by up to 30%.
Take levothyroxine on empty stomach; separate mineral supplements by at least 4 hours.
Suggested separation: 4 h
Compound-pair rule
Caution
Divalent cations chelate levothyroxine in the gut and reduce absorption by up to 30%.
Take levothyroxine on empty stomach; separate mineral supplements by at least 4 hours.
Suggested separation: 4 h
Frequently asked
Sources referenced
* Cochrane Library
* DrugBank
* Examine.com
* Mayo Clinic
* MedlinePlus
* National Institutes of Health Office of Dietary Supplements
* PubChem
Stackwise compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.
Related compounds
Others in the mineral category or studied for the same goals.