Calcium
Overview
Deep dive
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Known interactions
- Compound-pair ruleCaution
Calcium competes with iron for absorption, so taking large doses together reduces iron uptake.
Separate them by at least 2 hours.
Suggested separation: 2 h
- Compound-pair ruleCaution
High-dose calcium can reduce zinc absorption taken at the same time.
Separate by 2 hours if both are high-dose.
Suggested separation: 2 h
- Compound-pair ruleNote
Very large simultaneous doses can compete for absorption.
If both high-dose, splitting them can help.
- Compound-pair ruleCaution
Calcium reduces absorption of thyroid medication when taken together.
Separate by about 4 hours.
Suggested separation: 4 h
- Compound-pair ruleCaution
Divalent cations chelate levothyroxine in the gut and reduce absorption by up to 30%.
Take levothyroxine on empty stomach; separate mineral supplements by at least 4 hours.
Suggested separation: 4 h
- Compound-pair ruleCaution
Divalent cations chelate levothyroxine in the gut and reduce absorption by up to 30%.
Take levothyroxine on empty stomach; separate mineral supplements by at least 4 hours.
Suggested separation: 4 h
- Compound-pair ruleCaution
Minerals chelate T3 and reduce absorption.
Separate liothyronine and mineral supplements by at least 4 hours.
Suggested separation: 4 h
- Compound-pair ruleCaution
Calcium competes with iron for absorption.
Separate iron and calcium by at least 2 hours.
Suggested separation: 2 h
- Compound-pair ruleCaution
Divalent cations chelate levothyroxine in the gut and reduce absorption by up to 30%.
Take levothyroxine on empty stomach; separate mineral supplements by at least 4 hours.
Suggested separation: 4 h
- Compound-pair ruleCaution
Divalent cations chelate levothyroxine in the gut and reduce absorption by up to 30%.
Take levothyroxine on empty stomach; separate mineral supplements by at least 4 hours.
Suggested separation: 4 h
- Compound-pair ruleCaution
Minerals chelate T3 and reduce absorption.
Separate liothyronine and mineral supplements by at least 4 hours.
Suggested separation: 4 h
- Compound-pair ruleCaution
Calcium competes with iron for absorption.
Separate iron and calcium by at least 2 hours.
Suggested separation: 2 h
Frequently asked
Sources referenced
Stackwise compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.
Related compounds
Others in the mineral category or studied for the same goals.
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