Iron (ferrous bisglycinate)
Also known as: ferrous
Overview
Deep dive
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Known interactions
- Compound-pair ruleCaution
Calcium competes with iron for absorption, so taking large doses together reduces iron uptake.
Separate them by at least 2 hours.
Suggested separation: 2 h
- Compound-pair ruleSynergy
Vitamin C increases absorption of non-heme (supplement) iron.
Fine to take together; no need to separate.
- Compound-pair ruleCaution
Iron reduces absorption of thyroid medication when taken together.
Separate by about 4 hours.
Suggested separation: 4 h
- Compound-pair ruleCaution
Divalent cations chelate levothyroxine in the gut and reduce absorption by up to 30%.
Take levothyroxine on empty stomach; separate mineral supplements by at least 4 hours.
Suggested separation: 4 h
- Compound-pair ruleCaution
Divalent cations chelate levothyroxine in the gut and reduce absorption by up to 30%.
Take levothyroxine on empty stomach; separate mineral supplements by at least 4 hours.
Suggested separation: 4 h
- Compound-pair ruleCaution
Minerals chelate T3 and reduce absorption.
Separate liothyronine and mineral supplements by at least 4 hours.
Suggested separation: 4 h
- Compound-pair ruleCaution
Polyphenols in coffee/tea inhibit non-heme iron absorption by up to 60%.
Take iron away from coffee and tea by at least 2 hours.
Suggested separation: 2 h
- Compound-pair ruleCaution
Calcium competes with iron for absorption.
Separate iron and calcium by at least 2 hours.
Suggested separation: 2 h
- Compound-pair ruleCaution
Divalent cations chelate levothyroxine in the gut and reduce absorption by up to 30%.
Take levothyroxine on empty stomach; separate mineral supplements by at least 4 hours.
Suggested separation: 4 h
- Compound-pair ruleCaution
Divalent cations chelate levothyroxine in the gut and reduce absorption by up to 30%.
Take levothyroxine on empty stomach; separate mineral supplements by at least 4 hours.
Suggested separation: 4 h
- Compound-pair ruleCaution
Minerals chelate T3 and reduce absorption.
Separate liothyronine and mineral supplements by at least 4 hours.
Suggested separation: 4 h
- Compound-pair ruleCaution
Polyphenols in coffee/tea inhibit non-heme iron absorption by up to 60%.
Take iron away from coffee and tea by at least 2 hours.
Suggested separation: 2 h
- Compound-pair ruleCaution
Calcium competes with iron for absorption.
Separate iron and calcium by at least 2 hours.
Suggested separation: 2 h
- Compound-pair ruleSynergy
Vitamin C converts iron to more absorbable ferrous form.
Take iron with 200–500 mg vitamin C to boost absorption.
Frequently asked
Sources referenced
Stackwise compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.
Related compounds
Others in the mineral category or studied for the same goals.
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