medicationControlled

Dexmethylphenidate

Also known as: Focalin

Chemical structure of Dexmethylphenidate (PubChem CID 154101)
Structure via PubChem
Half-life
3 h
Typical timing
morning
Food rule
either
Default unit
mg

Studied for

Overview

Dexmethylphenidate, often known by its brand name Focalin, is a central nervous system (CNS) stimulant medication. It is primarily prescribed for the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) in both children and adults. It is the d-threo-isomer of methylphenidate, meaning it is one of the two mirror-image molecules (enantiomers) that make up racemic methylphenidate. Dexmethylphenidate is considered the more pharmacologically active component of methylphenidate. It is available in immediate-release and extended-release formulations. As a controlled substance, its use is regulated due to its potential for abuse and dependence. (FDA label, DrugBank)

Deep dive

Tap a section to expand.

Known interactions

  • Category rule: supplement × medication
    Note

    Some supplements change how the body processes medications (absorption, liver enzymes, or additive effects).

    Specific pairs are checked against a licensed drug database and shown with their own severity. Always confirm with your provider or pharmacist.

  • Category rule: vitamin × medication
    Note

    Certain vitamins interact with specific medications (e.g., vitamin K with blood thinners).

    Specific pairs are checked against a licensed source; confirm with your provider.

  • Compound-pair rule
    Avoid

    MAOI blocks catecholamine breakdown; combining with sympathomimetics can trigger hypertensive crisis.

    Do not combine.

  • Compound-pair rule
    Avoid

    MAOI blocks catecholamine breakdown; combining with sympathomimetics can trigger hypertensive crisis.

    Do not combine.

  • Compound-pair rule
    Avoid

    MAOI blocks catecholamine breakdown; combining with sympathomimetics can trigger hypertensive crisis.

    Do not combine.

Frequently asked

Sources referenced

["FDA label for Focalin and Focalin XR", "MedlinePlus - Dexmethylphenidate", "PubChem - Dexmethylphenidate", "DrugBank - Dexmethylphenidate", "Journal of the American Academy of Child and Adolescent Psychiatry (example journal type for evidence)"]

Stackwise compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.

Related compounds

Others in the medication category or studied for the same goals.

Related benefits

Other compounds studied for the same benefits as Dexmethylphenidate.

Continue exploring

See every compound Stackwise catalogues for these goals.

Track Dexmethylphenidate in Stackwise

Add it to your stack. We'll schedule doses, check interactions against everything else you take, and remind you at the right time.

Sign up free →