Reishi mushroom, scientifically known as *Ganoderma lucidum* or *Ganoderma lingzhi*, is a type of fungus that has been utilized in traditional medicine, particularly in Asia, for centuries. It is often referred to as the "mushroom of immortality" or "divine mushroom" due to its historical use in promoting health and longevity. Reishi mushrooms typically grow on decaying logs and tree stumps, particularly in warm, humid climates. While traditionally consumed as a hot water extract or tea, reishi is now widely available in various forms, including powders, capsules, and tinctures, as a dietary supplement.
The primary bioactive compounds identified in Reishi include triterpenes, polysaccharides (beta-glucans), peptidoglycans, and sterols. These compounds are believed to contribute to the mushroom's diverse biological activities. The exact composition and concentration of these compounds can vary significantly depending on the species of Ganoderma, cultivation methods, and processing techniques. Consumers considering reishi supplements often do so for general wellness, to support immune function, or for its alleged adaptogenic properties, which are thought to help the body adapt to stress.
Deep dive
Tap a section to expand.
Known interactions
Category rule: glp1 × supplement
Note
GLP-1 medications slow stomach emptying, changing how/when oral supplements absorb; rapid weight loss raises the importance of protein and micronutrients.
Time oral supplements when nausea is lowest; prioritize protein and micronutrients; discuss with your provider.
Category rule: supplement × medication
Note
Some supplements change how the body processes medications (absorption, liver enzymes, or additive effects).
Specific pairs are checked against a licensed drug database and shown with their own severity. Always confirm with your provider or pharmacist.
Sources referenced
* NIH Office of Dietary Supplements (ODS)
* MedlinePlus
* PubChem
* Mayo Clinic
* Examine.com
* Cochrane Library
Stackwise compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.
Related compounds
Others in the supplement category or studied for the same goals.