Krill oil is a dietary supplement derived from small, shrimp-like crustaceans called krill. It is primarily known for its rich content of omega-3 fatty acids, specifically eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Unlike fish oil, the omega-3s in krill oil are largely bound to phospholipids, which some research suggests may lead to better absorption by the body. Krill oil also contains astaxanthin, a potent antioxidant that gives krill their reddish-pink color. (NIH ODS, MedlinePlus)
Historically, krill have been a vital part of the marine food web, serving as a primary food source for whales, seals, and penguins. The extraction of krill for human consumption and supplementation began to gain traction in the late 20th and early 21st centuries. The sustainability of krill harvesting is a topic of ongoing discussion and regulation to ensure minimal impact on marine ecosystems. (Cochrane)
As a supplement, krill oil is marketed for various health benefits, particularly those related to cardiovascular health, cognitive function, and inflammation. Its profile of omega-3s, phospholipids, and astaxanthin distinguishes it from other omega-3 sources. (NIH ODS)
Deep dive
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Known interactions
Category rule: glp1 × supplement
Note
GLP-1 medications slow stomach emptying, changing how/when oral supplements absorb; rapid weight loss raises the importance of protein and micronutrients.
Time oral supplements when nausea is lowest; prioritize protein and micronutrients; discuss with your provider.
Category rule: supplement × medication
Note
Some supplements change how the body processes medications (absorption, liver enzymes, or additive effects).
Specific pairs are checked against a licensed drug database and shown with their own severity. Always confirm with your provider or pharmacist.
Discuss with prescribing clinician; monitor for bruising, prolonged bleeding, and dose adjustments.
Frequently asked
Sources referenced
["NIH Office of Dietary Supplements (ODS)", "MedlinePlus", "PubChem", "Mayo Clinic", "FDA label (general guidance for Omega-3 products)", "Cochrane Library", "DrugBank"]
Stackwise compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.
Related compounds
Others in the supplement category or studied for the same goals.