medication

Lansoprazole

Also known as: Prevacid

Chemical structure of Lansoprazole (PubChem CID 3883)
Structure via PubChem
Half-life
1.5 h
Typical timing
morning
Food rule
empty stomach
Default unit
mg

Overview

Lansoprazole is a medication classified as a proton pump inhibitor (PPI). It is primarily used to decrease the amount of acid produced in the stomach. Conditions treated with lansoprazole include gastroesophageal reflux disease (GERD), erosive esophagitis (damage to the esophagus from stomach acid), and Zollinger-Ellison syndrome (a condition where the body produces too much stomach acid). It can also be used in combination with antibiotics to treat *Helicobacter pylori* (H. pylori) infection, which can cause ulcers. As a PPI, lansoprazole works by irreversibly blocking the proton pumps in the stomach lining, which are responsible for the final step in acid production. This leads to a significant and sustained reduction in gastric acid secretion. Lansoprazole is available in various forms, including capsules, orally disintegrating tablets, and suspensions. It is typically taken once daily before a meal. Lansoprazole is available by prescription and also in lower doses as an over-the-counter (OTC) medication for the treatment of frequent heartburn. The duration of treatment varies depending on the condition being treated, ranging from a few weeks for acute conditions to long-term use for chronic acid production issues like Zollinger-Ellison syndrome.

Deep dive

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Known interactions

  • Category rule: supplement × medication
    Note

    Some supplements change how the body processes medications (absorption, liver enzymes, or additive effects).

    Specific pairs are checked against a licensed drug database and shown with their own severity. Always confirm with your provider or pharmacist.

  • Category rule: vitamin × medication
    Note

    Certain vitamins interact with specific medications (e.g., vitamin K with blood thinners).

    Specific pairs are checked against a licensed source; confirm with your provider.

  • Compound-pair rule
    Caution

    Reduced gastric acid impairs levothyroxine absorption.

    Monitor TSH after starting/stopping PPI; dose adjustment may be needed.

Frequently asked

Sources referenced

["Cochrane Library", "DrugBank", "EMA SmPC (European Medicines Agency Summary of Product Characteristics)", "FDA label (U.S. Food and Drug Administration)", "Mayo Clinic", "MedlinePlus", "NIH ODS (National Institutes of Health Office of Dietary Supplements)", "PubChem"]

Stackwise compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.

Related compounds

Others in the medication category or studied for the same goals.

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