Amitriptyline, commonly known by its former brand name Elavil, is a tricyclic antidepressant (TCA) medication. It was one of the first antidepressants developed and has been in use for several decades. While initially primarily prescribed for depression, its applications have expanded over time due to its diverse pharmacological properties. Today, it is also frequently used to manage various types of neuropathic pain, prevent migraines, and treat certain sleep disorders or functional bowel conditions. As a medication, its use requires careful consideration and professional medical guidance due to potential side effects and interactions. (DrugBank, Mayo Clinic)
Deep dive
Tap a section to expand.
Known interactions
Category rule: supplement × medication
Note
Some supplements change how the body processes medications (absorption, liver enzymes, or additive effects).
Specific pairs are checked against a licensed drug database and shown with their own severity. Always confirm with your provider or pharmacist.
Category rule: vitamin × medication
Note
Certain vitamins interact with specific medications (e.g., vitamin K with blood thinners).
Specific pairs are checked against a licensed source; confirm with your provider.
Frequently asked
Sources referenced
* Cochrane Library
* DrugBank
* Examine.com
* FDA Label Information
* Mayo Clinic
* MedlinePlus (NIH)
* National Institutes of Health (NIH)
* PubChem
Stackwise compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.
Related compounds
Others in the medication category or studied for the same goals.