medication

Amitriptyline

Also known as: Elavil

Chemical structure of Amitriptyline (PubChem CID 2160)
Structure via PubChem
Half-life
20 h
Typical timing
bedtime
Food rule
either
Default unit
mg

Overview

Amitriptyline, commonly known by its former brand name Elavil, is a tricyclic antidepressant (TCA) medication. It was one of the first antidepressants developed and has been in use for several decades. While initially primarily prescribed for depression, its applications have expanded over time due to its diverse pharmacological properties. Today, it is also frequently used to manage various types of neuropathic pain, prevent migraines, and treat certain sleep disorders or functional bowel conditions. As a medication, its use requires careful consideration and professional medical guidance due to potential side effects and interactions. (DrugBank, Mayo Clinic)

Deep dive

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Known interactions

  • Category rule: supplement × medication
    Note

    Some supplements change how the body processes medications (absorption, liver enzymes, or additive effects).

    Specific pairs are checked against a licensed drug database and shown with their own severity. Always confirm with your provider or pharmacist.

  • Category rule: vitamin × medication
    Note

    Certain vitamins interact with specific medications (e.g., vitamin K with blood thinners).

    Specific pairs are checked against a licensed source; confirm with your provider.

Frequently asked

Sources referenced

* Cochrane Library * DrugBank * Examine.com * FDA Label Information * Mayo Clinic * MedlinePlus (NIH) * National Institutes of Health (NIH) * PubChem

Stackwise compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.

Related compounds

Others in the medication category or studied for the same goals.

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