Pregabalin is a medication primarily prescribed for the management of neuropathic pain, fibromyalgia, and certain seizure disorders. It is also sometimes used for generalized anxiety disorder. Marketed under brand names such as Lyrica, it is an antiepileptic drug, also known as an anticonvulsant. While not an opioid, it exerts its effects on the central nervous system. It is considered a controlled substance in many regions due to its potential for misuse and dependence. The medication is typically taken orally in capsule or oral solution form. (MedlinePlus, FDA label)
Deep dive
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Known interactions
Category rule: supplement × medication
Note
Some supplements change how the body processes medications (absorption, liver enzymes, or additive effects).
Specific pairs are checked against a licensed drug database and shown with their own severity. Always confirm with your provider or pharmacist.
Category rule: vitamin × medication
Note
Certain vitamins interact with specific medications (e.g., vitamin K with blood thinners).
Specific pairs are checked against a licensed source; confirm with your provider.
Frequently asked
Sources referenced
- Cochrane Review
- DrugBank
- Examine.com
- European Medicines Agency (EMA) Summary of Product Characteristics (SmPC)
- U.S. Food and Drug Administration (FDA) label
- Mayo Clinic
- MedlinePlus
- National Institutes of Health (NIH) Office of Dietary Supplements (ODS)
Stackwise compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.
Related compounds
Others in the medication category or studied for the same goals.