uire pain management.

n I still feel pain if I'm on naltrexone? Yes, you can still feel pain. Naltrexone specifically blocks the effects of opioid pain relievers. Non-opioid pain relief options, such as NSAIDs (e.g., ibuprofen), acetaminophen, or other non-narcotic analgesics, are not affected by naltrexone and can be used to manage pain. It is crucial to inform your doctor that you are on naltrexone if you require pain management.

uently miss doses, discuss this with your healthcare provider.

t happens if I miss a dose of oral naltrexone? If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and resume your regular dosing schedule. Do not take two doses at once to make up for a missed dose. If you frequently miss doses, discuss this with your healthcare provider.

medication

Naltrexone (Full Dose)

Also known as: Vivitrol, ReVia

Half-life

4 h

Typical timing

morning

Food rule

either

Default unit

Overview

Naltrexone is a medication primarily used in the management of alcohol dependence and opioid dependence. It functions as an opioid antagonist, meaning it blocks the effects of opioid drugs. In the context of alcohol dependence, it is thought to reduce the craving for alcohol and the rewarding effects of drinking, thereby supporting abstinence or reducing heavy drinking. For opioid dependence, it prevents euphoric effects and helps maintain abstinence after detoxification. Naltrexone is available in oral tablet form and as an extended-release injectable formulation (Vivitrol). The full dose typically refers to the oral administration, which generally involves a higher daily amount compared to low-dose naltrexone (LDN). It is important to note that naltrexone is not a narcotic and is not addictive. It does not produce a euphoric effect. Treatment with naltrexone should always be part of a comprehensive management program that includes counseling and psychosocial support, as emphasized by the Substance Abuse and Mental Health Services Administration (SAMHSA).

Deep dive

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Known interactions

Category rule: supplement × medication
Note
Some supplements change how the body processes medications (absorption, liver enzymes, or additive effects).
Specific pairs are checked against a licensed drug database and shown with their own severity. Always confirm with your provider or pharmacist.
Category rule: vitamin × medication
Note
Certain vitamins interact with specific medications (e.g., vitamin K with blood thinners).
Specific pairs are checked against a licensed source; confirm with your provider.

Frequently asked

Sources referenced

* DrugBank * U.S. Food and Drug Administration (FDA) * National Institute on Alcohol Abuse and Alcoholism (NIAAA) * Substance Abuse and Mental Health Services Administration (SAMHSA) * Cochrane Database of Systematic Reviews * PubMed (for various clinical studies and reviews)

Stackwise compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.

Related compounds

Others in the medication category or studied for the same goals.

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Overview

Deep dive

How it works

Studied benefits

State of the evidence

Side effects

Warnings & who should avoid it

Contraindications

Do not mix with

Timing, food & half-life