peptide
N-Acetyl Semax Amidate
Also known as: NA-Semax, Semax Amidate
Half-life
1 h
Typical timing
morning
Food rule
either
Default unit
mg
Studied for
Overview
N-Acetyl Semax Amidate, often referred to as NA-Semax or Semax Amidate, is a synthetic peptide derived from adrenocorticotropic hormone (ACTH). It is a modified form of Semax, which is itself an analog of ACTH(4-10) with an additional Pro-Gly-Pro sequence. The N-acetyl and amidate modifications are introduced to potentially enhance its stability and bioavailability, influencing its interaction with the central nervous system. Semax peptides have been developed and studied in Russia, where Semax is used clinically. N-Acetyl Semax Amidate is not approved for medical use in many other countries, including the United States, and is typically available as a research chemical. Research into this peptide focuses on its potential neuroregulatory properties and its involvement in various brain functions, including those related to cognition and stress response (as noted by research literature in databases like PubChem).
Deep dive
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Known interactions
- Category rule: peptide × hormoneNote
Injectable peptides plus hormones can have overlapping or compounding effects that aren't always well characterized.
Track bloodwork with a provider; don't assume combinations are neutral.
Frequently asked
Sources referenced
* PubChem (National Center for Biotechnology Information)
* National Institutes of Health (NIH) research databases
* DrugBank Online
* Scientific literature from peer-reviewed journals (e.g., in fields of neuroscience, pharmacology, endocrinology)
* Examine.com (for general information on research compounds and related peptides)
* Review articles on peptide therapeutics and neuroactive compounds
Stackwise compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.
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