hormone
Ligandrol
Also known as: LGD-4033, Anabolicum
Half-life
30 h
Typical timing
any
Food rule
either
Default unit
mg
Studied for
Overview
Ligandrol, also known as LGD-4033 or Anabolicum, is a synthetic, non-steroidal selective androgen receptor modulator (SARM). SARMs are a class of therapeutic compounds that have similar anabolic properties to anabolic steroids but with reduced androgenic (masculinizing) properties. Ligandrol was developed by Ligand Pharmaceuticals and is currently being investigated for its potential in treating conditions such as muscle wasting and osteoporosis. (PubChem)
Unlike traditional anabolic steroids, which bind to androgen receptors throughout the body, SARMs like Ligandrol are designed to selectively bind to androgen receptors primarily in muscle and bone tissue. This selectivity aims to minimize unwanted side effects commonly associated with anabolic steroids, such as prostate enlargement, acne, hair loss, and liver toxicity. (DrugBank)
Despite its potential therapeutic applications, Ligandrol has gained popularity in athletic and bodybuilding communities as a performance-enhancing drug due to its purported ability to increase muscle mass and strength. However, it is not approved for human use by regulatory bodies like the U.S. Food and Drug Administration (FDA) for any medical condition, and its use in sports is prohibited by organizations such as the World Anti-Doping Agency (WADA). (FDA, WADA website)
Research on Ligandrol is ongoing, with studies exploring its efficacy and safety profile. Early clinical trials have shown promising results in increasing lean body mass and muscle strength in healthy men. However, long-term safety data and a complete understanding of its side effects are still under investigation. (PubChem)
Deep dive
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Known interactions
- Category rule: peptide × hormoneNote
Injectable peptides plus hormones can have overlapping or compounding effects that aren't always well characterized.
Track bloodwork with a provider; don't assume combinations are neutral.
Frequently asked
Sources referenced
["U.S. Food and Drug Administration (FDA)", "National Institutes of Health Office of Dietary Supplements (NIH ODS)", "MedlinePlus (National Library of Medicine)", "PubChem (National Library of Medicine)", "DrugBank (University of Alberta)", "World Anti-Doping Agency (WADA) website"]
Stackwise compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.
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Related benefits
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