hormone
DHEA
Also known as: Dehydroepiandrosterone
Half-life
25 h
Typical timing
morning
Food rule
either
Default unit
mg
Studied for
Overview
Dehydroepiandrosterone (DHEA) is a steroid hormone naturally produced by the adrenal glands, gonads, and brain. It is the most abundant circulating steroid hormone in humans. DHEA serves as a precursor to other steroid hormones, including androgens (like testosterone) and estrogens (like estradiol). Levels of DHEA naturally peak in early adulthood and decline with age. Interest in DHEA as a supplement stems from its potential to counteract age-related declines in hormone levels and its widespread presence in the body. While DHEA is available as a dietary supplement in some countries, its classification can vary, and its use is subject to different regulations globally. (NIH ODS, DrugBank)
Deep dive
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Known interactions
- Category rule: peptide × hormoneNote
Injectable peptides plus hormones can have overlapping or compounding effects that aren't always well characterized.
Track bloodwork with a provider; don't assume combinations are neutral.
Sources referenced
- NIH Office of Dietary Supplements (ODS)
- DrugBank
- PubChem
- Mayo Clinic
- MedlinePlus
- Cochrane Library
Stackwise compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.
Related compounds
Others in the hormone category or studied for the same goals.
Related benefits
Other compounds studied for the same benefits as DHEA.
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