hormoneInjectableControlled
Drostanolone Propionate
Also known as: Masteron
Half-life
48 h
Typical timing
any
Food rule
either
Default unit
mg
Studied for
Overview
Drostanolone propionate, commonly known by its brand name Masteron, is a synthetic anabolic androgenic steroid (AAS) derived from dihydrotestosterone (DHT). It is characterized by the addition of a methyl group at the carbon 2 position, which enhances its anabolic properties and makes it resistant to metabolic breakdown in the body. The propionate ester attached to drostanolone regulates its release rate, resulting in a half-life of approximately 48 hours.
Historically, drostanolone propionate found medical application in the treatment of breast cancer in postmenopausal women. However, due to the availability of more effective and less virilizing treatments, its clinical use for this purpose has largely ceased. Today, its use is primarily within the realm of performance enhancement, particularly among bodybuilders and athletes.
Drostanolone is recognized for its unique profile among anabolic steroids. It possesses moderate anabolic and low androgenic properties, and notably, it is not aromatized into estrogen. This characteristic is a key differentiator, as it prevents estrogen-related side effects such as gynecomastia (enlargement of male breast tissue) and water retention, which are common with many other anabolic steroids. This makes it particularly favored during cutting cycles, where the goal is to reduce body fat while preserving muscle mass, often leading to a 'harder' and more defined physique.
Despite its perceived benefits in performance enhancement circles, it is a highly controlled substance and its non-medical use is illegal in most countries. It carries significant risks and potential side effects, similar to other anabolic androgenic steroids. Its use should be under strict medical supervision due to its controlled status and potential health implications. (DrugBank, PubChem)
Deep dive
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Known interactions
- Category rule: peptide × hormoneNote
Injectable peptides plus hormones can have overlapping or compounding effects that aren't always well characterized.
Track bloodwork with a provider; don't assume combinations are neutral.
Frequently asked
Sources referenced
["DrugBank: Drostanolone", "PubChem: Drostanolone", "FDA label information for Masteron (historical data)", "MedlinePlus - Anabolic Steroids"]
Stackwise compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.
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Related benefits
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