peptideInjectable

GHRH (1-29)

Also known as: GRF

Chemical structure of GHRH (1-29) (PubChem CID 16132412)
Structure via PubChem
Half-life
0.2 h
Typical timing
bedtime
Food rule
either
Default unit
mcg

Studied for

Overview

GHRH (1-29), also known as Growth Hormone-Releasing Hormone (1-29) or Sermorelin, is a synthetic peptide fragment representing the first 29 amino acids of endogenous human Growth Hormone-Releasing Hormone (GHRH). It is classified as a secretagogue because it stimulates the pituitary gland to release its own growth hormone (GH) in a pulsatile, natural manner. Unlike direct administration of synthetic growth hormone, GHRH (1-29) encourages the body's natural physiological production and release of GH, which in turn can lead to increased levels of insulin-like growth factor-1 (IGF-1). The regulation of GH and IGF-1 is critical for many physiological processes, including body composition, metabolism, and cellular repair. Due to its short half-life and natural mode of action, GHRH (1-29) has been investigated for various applications, particularly those related to growth hormone deficiency, muscle development, and recovery processes. It is typically administered via subcutaneous injection. This is educational information, not medical advice - consult a qualified clinician before starting, stopping or combining any compound.

Deep dive

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Known interactions

  • Category rule: peptide × hormone
    Note

    Injectable peptides plus hormones can have overlapping or compounding effects that aren't always well characterized.

    Track bloodwork with a provider; don't assume combinations are neutral.

Frequently asked

Sources referenced

* DrugBank * FDA label (Sermorelin) * MedlinePlus * NIH Office of Dietary Supplements (ODS) * PubChem * PubMed (various research articles on GHRH, GH, and IGF-1 biology)

Stackwise compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.

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