medication

Dutasteride

Also known as: Avodart

Chemical structure of Dutasteride (PubChem CID 6918296)
Structure via PubChem
Half-life
1200 h
Typical timing
any
Food rule
either
Default unit
mg

Overview

Dutasteride is a medication primarily prescribed for the management of benign prostatic hyperplasia (BPH), also known as an enlarged prostate, and for male pattern hair loss (androgenetic alopecia). It belongs to a class of drugs called 5-alpha-reductase inhibitors. Its action involves reducing the levels of dihydrotestosterone (DHT), a potent androgen hormone that plays a key role in the development of BPH and hair loss. Dutasteride is available in oral capsule form and is often marketed under the brand name Avodart. It is typically used long-term due to its mechanism of action and the chronic nature of the conditions it treats. The dose is user-directed and must be set by a licensed clinician.

Deep dive

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Known interactions

  • Category rule: supplement × medication
    Note

    Some supplements change how the body processes medications (absorption, liver enzymes, or additive effects).

    Specific pairs are checked against a licensed drug database and shown with their own severity. Always confirm with your provider or pharmacist.

  • Category rule: vitamin × medication
    Note

    Certain vitamins interact with specific medications (e.g., vitamin K with blood thinners).

    Specific pairs are checked against a licensed source; confirm with your provider.

  • Compound-pair rule
    Caution

    5-alpha-reductase inhibitors block DHT conversion; can affect libido and prostate response on TRT.

    Discuss goals with prescribing clinician; monitor sexual function.

Frequently asked

Sources referenced

["U.S. Food and Drug Administration (FDA) - Avodart (dutasteride) Label", "National Institutes of Health (NIH) Office of Dietary Supplements (ODS)", "PubChem - National Library of Medicine", "DrugBank Online", "European Medicines Agency (EMA) - Summary of Product Characteristics (SmPC)", "Cochrane Database of Systematic Reviews", "Journal of the American Academy of Dermatology"]

Stackwise compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.

Related compounds

Others in the medication category or studied for the same goals.

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