peptideInjectableControlled

CJC-1295

Chemical structure of CJC-1295 (PubChem CID 91971820)
Structure via PubChem
Half-life
Typical timing
bedtime
Food rule
empty stomach
Default unit
mcg

Studied for

Overview

CJC-1295 is a synthetic peptide classified as a Growth Hormone-Releasing Hormone (GHRH) analog. It was originally developed with the intention of treating medical conditions such as lipodystrophy, a disorder characterized by abnormal fat distribution, and growth hormone deficiency. Its primary action is to stimulate the release of growth hormone (GH) from the pituitary gland. Unlike naturally occurring GHRH, CJC-1295 incorporates a Drug Affinity Complex (DAC) technology which allows it to have a much longer half-life, meaning it remains active in the body for an extended period compared to natural GHRH. This prolonged action reduces the frequency of administration needed. It is not currently approved by the FDA for human use and is considered a research chemical, often found in contexts related to bodybuilding and anti-aging, though its safety and efficacy for these uses are not established. CJC-1295 is an injectable compound and is classified as controlled, meaning its use must be directed by a licensed clinician.

Deep dive

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Known interactions

  • Compound-pair rule
    Caution

    A GH secretagogue plus exogenous IGF-1 pushes the same GH/IGF-1 axis from two directions; redundant and can overstimulate with feedback effects.

    Treat as same-axis stacking; needs provider oversight and a clear rationale.

  • Compound-pair rule
    Note

    Commonly combined GH secretagogues that act on complementary receptors; frequently stacked intentionally rather than redundantly.

    Often used together on purpose; still provider-supervised territory.

  • Compound-pair rule
    Caution

    Two GHRH-type analogs push the same node of the axis; redundant.

    Same-axis redundancy; usually pick one.

  • Category rule: peptide × hormone
    Note

    Injectable peptides plus hormones can have overlapping or compounding effects that aren't always well characterized.

    Track bloodwork with a provider; don't assume combinations are neutral.

Frequently asked

Sources referenced

["National Institutes of Health (NIH) Office of Dietary Supplements (ODS)", "MedlinePlus (U.S. National Library of Medicine)", "PubChem (National Library of Medicine)", "DrugBank"]

Stackwise compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.

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Related benefits

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