vitamin

Vitamin B9 (Folate)

Also known as: 5-MTHF, Methylfolate

Half-life
3 h
Typical timing
morning
Food rule
either
Default unit
mcg

Studied for

Overview

Vitamin B9, commonly known as folate, is a water-soluble vitamin essential for numerous bodily functions. It plays a critical role in one-carbon metabolism, which is involved in DNA synthesis and repair, red blood cell production, and the metabolism of amino acids. Folate is naturally present in many foods, particularly dark leafy green vegetables, fruits, nuts, beans, peas, and enriched grain products. The synthetic form of folate, called folic acid, is often used in dietary supplements and fortified foods. Adequate folate intake is vital throughout life, especially during periods of rapid cell growth such as pregnancy and infancy. Deficiency can lead to various health issues, including megaloblastic anemia and, in pregnant individuals, neural tube defects in the developing fetus. The body does not store large amounts of folate, so regular intake through diet or supplementation is necessary (NIH ODS).

Deep dive

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Known interactions

  • Category rule: vitamin × medication
    Note

    Certain vitamins interact with specific medications (e.g., vitamin K with blood thinners).

    Specific pairs are checked against a licensed source; confirm with your provider.

Frequently asked

Sources referenced

- NIH Office of Dietary Supplements (ODS) - MedlinePlus - PubChem - Mayo Clinic - Cochrane Library - Examine.com - DrugBank

Stackwise compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.

Related compounds

Others in the vitamin category or studied for the same goals.

Related benefits

Other compounds studied for the same benefits as Vitamin B9 (Folate).

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