Ramelteon, marketed under the brand name Rozerem, is a medication approved by the U.S. Food and Drug Administration (FDA) for the treatment of insomnia characterized by difficulty with sleep onset. Unlike some other sleep medications, ramelteon is not classified as a controlled substance, meaning it has a lower potential for abuse and dependence. Its mechanism of action is distinct from benzodiazepines and non-benzodiazepine hypnotics, primarily targeting melatonin receptors in the brain. It is typically taken shortly before bedtime. (Source: FDA label, DrugBank)
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Known interactions
Category rule: supplement × medication
Note
Some supplements change how the body processes medications (absorption, liver enzymes, or additive effects).
Specific pairs are checked against a licensed drug database and shown with their own severity. Always confirm with your provider or pharmacist.
Category rule: vitamin × medication
Note
Certain vitamins interact with specific medications (e.g., vitamin K with blood thinners).
Specific pairs are checked against a licensed source; confirm with your provider.
Frequently asked
Sources referenced
* U.S. Food and Drug Administration (FDA)
* DrugBank
* PubChem
* National Institutes of Health (NIH)
* Cochrane Library
* Mayo Clinic
Stackwise compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.
Related compounds
Others in the medication category or studied for the same goals.
