peptideInjectable
Pralmorelin
Also known as: GHRP-2 acetate
Half-life
1 h
Typical timing
any
Food rule
either
Default unit
mcg
Studied for
Overview
Pralmorelin, also known by its research name GHRP-2 acetate, is a synthetic peptide belonging to the growth hormone-releasing peptide (GHRP) family. It was developed to stimulate the secretion of growth hormone (GH) from the pituitary gland. Unlike growth hormone-releasing hormone (GHRH), which acts on specific GHRH receptors, pralmorelin exerts its effects by binding to ghrelin/growth hormone secretagogue receptors (GHSRs). These receptors are found in various tissues throughout the body, including the pituitary gland and the hypothalamus. The stimulation of these receptors leads to a pulsatile release of growth hormone. Pralmorelin is not a controlled substance and has been studied for various potential applications due to its potent GH-releasing capabilities. It is typically administered via injection.
The development of GHRPs like pralmorelin aimed to identify compounds that could act independently of, or synergistically with, endogenous GHRH to enhance GH secretion, offering potential therapeutic avenues for conditions characterized by GH deficiency or catabolic states (PubChem, DrugBank).
Deep dive
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Known interactions
- Category rule: peptide × hormoneNote
Injectable peptides plus hormones can have overlapping or compounding effects that aren't always well characterized.
Track bloodwork with a provider; don't assume combinations are neutral.
Frequently asked
Sources referenced
["PubChem","DrugBank peptides","NIH ODS (Office of Dietary Supplements)","MedlinePlus","Mayo Clinic consensus statements","Cochrane Library systematic reviews","Examine.com research reviews","Endocrine Society journals"]
Stackwise compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.
Related compounds
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Related benefits
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