How quickly does Losartan start working?**

rtan start working?** A: While some blood pressure reduction may be seen within a few hours of the first dose, the full blood pressure-lowering effect of losartan typically develops over several weeks of consistent use (Mayo Clinic).

Can Losartan cause a cough?**

n Losartan cause a cough?** A: While ACE inhibitors are known for causing a dry cough, Losartan (an ARB) is generally associated with a lower incidence of cough. However, some people might still experience a cough as a side effect (MedlinePlus).

What if I miss a dose of Losartan?**

t if I miss a dose of Losartan?** A: If you miss a dose, take it as soon as you remember unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. Always consult your prescribing clinician for specific advice.

Can Losartan be taken with food?**

n Losartan be taken with food?** A: Yes, Losartan can be taken with or without food. It is generally recommended to take it at the same time each day for optimal effectiveness.

medication

Losartan

Also known as: Cozaar

Structure via PubChem

Half-life

2 h

Typical timing

morning

Food rule

either

Default unit

Overview

Losartan is an angiotensin II receptor blocker (ARB) medication. It is primarily used to treat high blood pressure (hypertension), reduce the risk of stroke in patients with high blood pressure and an enlarged heart, and manage kidney disease in people with type 2 diabetes and a history of high blood pressure (as described by the FDA label). Losartan is available as an oral tablet and is often taken once daily. It was first approved for medical use in the United States in 1995. The medication works by blocking the action of a naturally occurring substance in the body called angiotensin II, which narrows blood vessels and plays a role in blood pressure regulation.

Deep dive

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Known interactions

Category rule: supplement × medication
Note
Some supplements change how the body processes medications (absorption, liver enzymes, or additive effects).
Specific pairs are checked against a licensed drug database and shown with their own severity. Always confirm with your provider or pharmacist.
Category rule: vitamin × medication
Note
Certain vitamins interact with specific medications (e.g., vitamin K with blood thinners).
Specific pairs are checked against a licensed source; confirm with your provider.
Compound-pair rule
Caution
PDE5 inhibitors add to the blood-pressure-lowering effect of antihypertensives.
Start PDE5 at the lowest effective dose and monitor for hypotension.
Compound-pair rule
Caution
PDE5 inhibitors add to the blood-pressure-lowering effect of antihypertensives.
Start PDE5 at the lowest effective dose and monitor for hypotension.
Compound-pair rule
Caution
PDE5 inhibitors add to the blood-pressure-lowering effect of antihypertensives.
Start PDE5 at the lowest effective dose and monitor for hypotension.

Frequently asked

Sources referenced

- U.S. Food and Drug Administration (FDA) - Mayo Clinic - MedlinePlus (National Library of Medicine) - National Institutes of Health (NIH) - NIDDK (National Institute of Diabetes and Digestive and Kidney Diseases) - Cochrane Library - DrugBank

Stackwise compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.

Related compounds

Others in the medication category or studied for the same goals.

Track Losartan in Stackwise

Add it to your stack. We'll schedule doses, check interactions against everything else you take, and remind you at the right time.

Overview

Deep dive

How it works

Studied benefits

State of the evidence

Side effects

Warnings & who should avoid it

Contraindications

Do not mix with

Timing, food & half-life