medication

Enalapril

Also known as: Vasotec

Chemical structure of Enalapril (PubChem CID 5388962)
Structure via PubChem
Half-life
11 h
Typical timing
morning
Food rule
either
Default unit
mg

Overview

Enalapril is a medication belonging to the class of drugs known as angiotensin-converting enzyme (ACE) inhibitors. It is primarily used to treat high blood pressure (hypertension), heart failure, and to prevent kidney problems in people with diabetes. Enalapril works by relaxing blood vessels, which helps to lower blood pressure and improve blood flow. It is available as an oral tablet and is also marketed under the brand name Vasotec. Like other ACE inhibitors, Enalapril is a prodrug, meaning it is inactive until metabolized in the body. Its active form, enalaprilat, is responsible for the therapeutic effects. Enalapril is often prescribed as a long-term treatment for chronic conditions and requires regular monitoring by a healthcare provider. (NIH ODS, DailyMed)

Deep dive

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Known interactions

  • Category rule: supplement × medication
    Note

    Some supplements change how the body processes medications (absorption, liver enzymes, or additive effects).

    Specific pairs are checked against a licensed drug database and shown with their own severity. Always confirm with your provider or pharmacist.

  • Category rule: vitamin × medication
    Note

    Certain vitamins interact with specific medications (e.g., vitamin K with blood thinners).

    Specific pairs are checked against a licensed source; confirm with your provider.

  • Compound-pair rule
    Caution

    PDE5 inhibitors add to the blood-pressure-lowering effect of antihypertensives.

    Start PDE5 at the lowest effective dose and monitor for hypotension.

  • Compound-pair rule
    Caution

    PDE5 inhibitors add to the blood-pressure-lowering effect of antihypertensives.

    Start PDE5 at the lowest effective dose and monitor for hypotension.

  • Compound-pair rule
    Caution

    PDE5 inhibitors add to the blood-pressure-lowering effect of antihypertensives.

    Start PDE5 at the lowest effective dose and monitor for hypotension.

Frequently asked

Sources referenced

["NIH ODS (National Institutes of Health Office of Dietary Supplements)", "MedlinePlus (National Library of Medicine)", "PubChem (National Library of Medicine)", "Mayo Clinic", "FDA label (U.S. Food and Drug Administration)", "EMA SmPC (European Medicines Agency Summary of Product Characteristics)", "Cochrane (Cochrane Library)", "DrugBank (University of Alberta)", "DailyMed (National Library of Medicine)"]

Stackwise compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.

Related compounds

Others in the medication category or studied for the same goals.

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