Tamoxifen, often marketed under the brand name Nolvadex, is a medication primarily used to treat and prevent certain types of breast cancer. It belongs to a class of drugs known as selective estrogen receptor modulators (SERMs). For breast cancer, tamoxifen is indicated for estrogen receptor (ER)-positive breast cancer. It works by blocking the effects of estrogen in breast tissue, which can help stop the growth of ER-positive cancer cells. Its use extends to both early-stage and advanced breast cancer, as well as for reducing the risk of breast cancer in high-risk individuals. Tamoxifen is an oral medication, typically taken once or twice daily. (Source: FDA label, DrugBank)
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Known interactions
Category rule: supplement × medication
Note
Some supplements change how the body processes medications (absorption, liver enzymes, or additive effects).
Specific pairs are checked against a licensed drug database and shown with their own severity. Always confirm with your provider or pharmacist.
Category rule: vitamin × medication
Note
Certain vitamins interact with specific medications (e.g., vitamin K with blood thinners).
Specific pairs are checked against a licensed source; confirm with your provider.
Sources referenced
* FDA label (specific product inserts for Tamoxifen)
* DrugBank (www.drugbank.ca)
* PubChem (pubchem.ncbi.nlm.nih.gov)
* National Cancer Institute (www.cancer.gov)
* Mayo Clinic (www.mayoclinic.org)
* Cochrane Library (www.cochranelibrary.com)
* The Lancet (www.thelancet.com)
* Journal of the National Cancer Institute (academic.oup.com/jnci)
Stackwise compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.
Related compounds
Others in the medication category or studied for the same goals.
