Cinnamon extract is derived from the bark of various cinnamon trees, primarily *Cinnamomum cassia* (also known as Chinese cinnamon or Saigon cinnamon) and *Cinnamomum verum* (Ceylon cinnamon). Historically, cinnamon has been used as a spice, a traditional medicine, and a food preservative across many cultures, particularly in East and South Asia. The active compounds responsible for its potential health effects include cinnamaldehyde, cinnamic acid, and coumarin, along with various polyphenols. While *C. cassia* is more commonly found and studied in supplements, it naturally contains higher levels of coumarin compared to *C. verum*. Coumarin is a substance that can be harmful to the liver in large doses. Ceylon cinnamon is often considered the 'true' cinnamon and has very low levels of coumarin, making it a safer option for regular or high-dose consumption. Supplements typically concentrate these compounds, aiming to deliver higher therapeutic levels than what might be obtained from culinary use alone. Cinnamon extract is commonly used as a dietary supplement for various health purposes, with a particular focus on metabolic health.
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Known interactions
Category rule: glp1 × supplement
Note
GLP-1 medications slow stomach emptying, changing how/when oral supplements absorb; rapid weight loss raises the importance of protein and micronutrients.
Time oral supplements when nausea is lowest; prioritize protein and micronutrients; discuss with your provider.
Category rule: supplement × medication
Note
Some supplements change how the body processes medications (absorption, liver enzymes, or additive effects).
Specific pairs are checked against a licensed drug database and shown with their own severity. Always confirm with your provider or pharmacist.
Stackwise compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.
Related compounds
Others in the supplement category or studied for the same goals.
