Vitamin D2, also known as ergocalciferol, is one of two primary forms of vitamin D, the other being vitamin D3 (cholecalciferol). Both D2 and D3 are prohormones that the body converts into calcitriol, the active form of vitamin D. Vitamin D2 is primarily found in plant-based sources like fortified foods (e.g., milk, cereals, orange juice) and some mushrooms exposed to ultraviolet (UV) light. It can also be produced synthetically. The historical discovery of vitamin D was linked to finding a cure for rickets, a bone-softening disease prevalent in children during the early 20th century. Ergocalciferol was identified as the anti-rachitic factor derived from irradiated ergosterol. Its fundamental role in calcium and phosphate homeostasis underscores its importance for bone health and various other physiological processes. (NIH ODS data)
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Known interactions
Category rule: vitamin × medication
Note
Certain vitamins interact with specific medications (e.g., vitamin K with blood thinners).
Specific pairs are checked against a licensed source; confirm with your provider.
Frequently asked
Sources referenced
["NIH Office of Dietary Supplements (ODS)","MedlinePlus (National Library of Medicine)","PubChem (National Center for Biotechnology Information)","Mayo Clinic","Cochrane Library","Examine.com","DrugBank"]
Stackwise compiles summaries from publicly available scientific and regulatory references. Always verify important decisions with a licensed clinician.
Related compounds
Others in the vitamin category or studied for the same goals.